Preparation and Characterization of Amino Acetylene Derivative by  Mannich Reaction

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DC Field	Value	Language
dc.contributor.author	TAREQ .A. MANDEEL, MANAF.A. GUMA.	-
dc.date.accessioned	2022-10-16T07:40:51Z	-
dc.date.available	2022-10-16T07:40:51Z	-
dc.date.issued	2013	-
dc.identifier.issn	2222-8373	-
dc.identifier.uri	http://localhost:8080/xmlui/handle/123456789/1745	-
dc.description.abstract	A short procedure for preparation of {4-[17-(1,5-Dimethyl-hexyl)-10,13-dimethyl hexadecahydro-cyclopenta[a]phenanthren-3-yloxy] –but -2-ynylamino}-acetaldehyde)(3) from reaction of terminal acetylene with N-(diphenylmethylene) glycinates (2) is described. The reaction of terminal acetylene with compound (2) promoted by amino acid gave the dehydroamino acids containing secondary amine in good yield with aldehyde in presence of CuCl via microwave technique according to Mannich reaction .The compound(2) was prepared by refluxing cholesterol with propargyl bromide in dilute ethanolic potassium hydroxide solution at 70 oC .All compounds were characterized by means of their FT.IR spectra data and melting points.	en_US
dc.publisher	DIYALA JOURNAL FOR PURE SCIENCES	en_US
dc.subject	Mannich reaction	en_US
dc.subject	Terminal acetylene	en_US
dc.subject	SN2 mechanism	en_US
dc.subject	cholesterol	en_US
dc.title	Preparation and Characterization of Amino Acetylene Derivative by Mannich Reaction	en_US
dc.type	Other	en_US
Appears in Collections:	قسم الفيزياء الحياتية

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