GREEN SYNTHESIS OF AuNPs FROM THE LEAF EXTRACT OF PROSOPIS FARCTA FOR ANTIBACTERIAL AND ANTI-CANCER APPLICATIONS

Abstract

This study involves the synthesis of gold nanoparticles (AuNPs) formed from the Prosopis farcta leaf extract. The transmission electron microscope, scanning electron microscope, atomic force microscope, X-ray diffraction, and UV-Visible spectroscopy results all confirmed the characterisation of AuNPs. The in vitro anticancer activity of AuNPs against breast cancer -13 (AMJ-13) and human breast epithelial (HBL) cell lines was investigated, along with its antibacterial activity against gram's positive bacteria, the Staphylococcus aureus. AuNPs were found to produce a significant cytotoxic effect on the AMJ-13 cell line, contrary to the HBL cell line, which showed no significant cytotoxicity upon it. The antibacterial activity demonstrated that gram-positive S. aureus was affected by AuNPs. These results prove that AuNPs have great potential as anticancer and antibacterial agents and can be used in developing strategies for successful anticancer and antibacterial.