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Title: | Synthesis and characterization of orotic acid loaded chitosan inclusion complex |
Authors: | H. ENEZE, Hamid |
Keywords: | Chitosan Drug delivery |
Issue Date: | 27-Apr-2020 |
Publisher: | Hassani, Abdelkader and Azad, Abul Kalam and Enezei, Hamid H. and Hussain, Siti A. and Helal Uddin, Abul Bashar Mohammed |
Abstract: | The current study aims to improve drug release properties of orotic acid loaded with chitosan inclusion complex (OA/CS). The OA/CS inclusion complex was synthesized using the freeze-drying technique. The characterization of inclusion OA/ CS was carried out using fourier transform infrared spectroscopy (FTIR), X-ray diffractometry (XRD), differential scanning calorimetry (DSC), zeta sizer, and transmission electron microscopy (TEM). Furthermore, the size of OA/CS ranged between 58 nm and 200 nm, and the zeta potential was 30 mV. Thus, this study indicates that OA/CS has a promising future to develop a carrier for drug delivery systems further. |
URI: | http://localhost:8080/xmlui/handle/123456789/2314 |
Appears in Collections: | كلية طب الاسنان |
Files in This Item:
File | Description | Size | Format | |
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82571_Synthesis and characterization of orotic acid loaded chitosan inclusion complex.pdf | 318.2 kB | Adobe PDF | View/Open |
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