Preparation, Diagnoses of novel hetero atom compounds and Evaluation the Antibacterial Activity of them

Abstract

This work included prepare of hetero atom compounds Ra1-Ra5from the interaction of prepared azomethines with anhydride compound. Azomethine compounds were prepared by condensation reaction. A number of new hetero atom compounds were prepared by acid-catalyzed Cycloaddition - reaction in anhydrous THF under reflux conditions. The formation of hetero ring has been achieved by Cycloaddition. The melting point, 1H NMR, FT-IR and 13C-NMRspectroscopies technique were used to identified the final products. Biological activity of the prepared hetero compoundsRa1-Ra5evaluated on E. Coli and S. aureus.