Please use this identifier to cite or link to this item: http://localhost:8080/xmlui/handle/123456789/3203
Full metadata record
DC FieldValueLanguage
dc.contributor.authorAl-Obaidi, Omar H.-
dc.date.accessioned2022-10-19T13:34:00Z-
dc.date.available2022-10-19T13:34:00Z-
dc.date.issued2017-
dc.identifier.issn2376-7782-
dc.identifier.urihttp://localhost:8080/xmlui/handle/123456789/3203-
dc.description.abstractThe new complexes of Cr(III), Mn (II), Fe(III) and Cu(II) complexes with the chalcone ligand were studied on the growth of Rhabdomyo sarcomas (RD) cell Line in human by using in vitro system and compared with anticancer drug cis platin (cis-pt) as appositive control. The cancer cells were treated with different concentration and cis-pt after 72 hr. exposure time. The cytotoxic activity was tested by inhibition rate as parameter. The results showed significant differences (p<0.05) for each three treatments when the inhibition rates were increased. The synthesized compounds were tested for antimicrobial activity by cup plate diffusion method. The results indicate the enhanced activity of metal complexes over the parent ligands. The synthesized complexes have been screened for in vitro antibacterial activity against Escherichia coli and Staphylococcus aureus, and new prepared complexes were compared with anticancer drug cis-platin.en_US
dc.language.isoenen_US
dc.publisherJournal of Cancer Treatment and Researchen_US
dc.subjectChalcone, Complexes, Antimicrobial Activity, Cytotoxicity Cisplatinen_US
dc.titleStudy of the Cytotoxicity Effect of New Cr(III), Mn(II), Fe(III) and Cu(II) Complexes of Chalcone on Cancer (Cell Line RD) and Antimicribial Activityen_US
dc.typeArticleen_US
Appears in Collections:قسم الكيمياء

Files in This Item:
File Description SizeFormat 
Study of the Cytotoxicity Effect of New Cr(III), Mn(II), Fe(III).pdf616.5 kBAdobe PDFView/Open


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.