Renal Function Status of Fallujah Patients (IRAQ) Infected with Chronic Hepatitis B

Abstract

The present study focuses on the kidney function in patients with chronic hepatitis B. The patients were divided into two groups including patients with chronic hepatitis B; some of the patients were HBSAg positive, HBeAg positive and HBeAb negative; others were HBSAg positive, HBeAg negative and HBeAb positive. The results were compared to those of healthy individuals. There were about sixty patients with chronic hepatitis B and thirty healthy individuals. Transaminases (AST and ALT) enzymes activities in patients, T.S.B and amount of albumin in addition to serum electrolyte, urea and creatinine were measured using standard laboratory methods. Viral load (HBV PCR) was also measured in patients. Results from this study showed low serum albumin and higher serum urea and creatinine with chronic hepatitis B compared to those of healthy individuals. Serum potassium, chloride and phosphorus concentration were higher in the patients with chronic hepatitis B compared to those of healthy individuals (5.25389±.78565 )( 6.518±.58370); and in comparison to healthy individuals (4.5185 ±.33948) while chloride measures (101.4±10.2682), (104.2821±19.63813) compared to healthy individuals (100.4133±8.32457) while phosphorus measured (36±5.88) (35.6283±11.6) compared to healthy individuals (34.7100±5 ).While serum sodium was significantly low in patients with chronic hepatitis B compared to those of healthy individuals (143±7.144±6.76) and compared to healthy individuals (145±6.89).The results from this study showed a possible relationship between hepatitis B infection and insufficient renal function.