Enhancement of Wounds Healing by Atmospheric Non-Thermal Plasma on Iraqi Patients

Abstract

Non-thermal atmospheric pressure plasma has emerged as a new promising tool in medicine. The effectiveness of an Atmospheric Non Thermal Plasma (ANTP) for clinical and biological applications is studied. This research effort includes a designing of plasma generating system and examine it on some medical and biological parameters. No patient had previous operative or chemotherapeutic treatment, so the patients with hematological disorders (hemophilia) and those with open heart surgery that receiving warfarin and other antithrombotic agents were excluded from the study. A total of eighty (80) Iraqi patients seeking for a medical consultation in Al-Ramadi Teaching Hospital were included in this study. The plasma treatment is applied both in vitro and in vivo experiments on those patients. In the in vivo experiments, the bleeding time (BT) tests were carried out on these patients; the results showed the BT of the patients was reduced as compared with control. In vitro experiments regarding clotting time (CT). The results have demonstrated that this plasma device clots blood rapidly via a (control). The dependencies of the degree of clotting on the exposure time, distance have been recorded. A series of experiments reveal that this effectiveness is due to the ability of direct discharge to bring ions to blood samples due to generation of so many mediators like reactive nitrogen species and free radicals. Introduction: Plasma in physics is the fourth state of matter and most in the universe, as fire in the sun, stars [1], while .This term was introduced by Irving Langmuir in 1928, because it resembles the ionic liquids in medicine and biology, it consists of positively and negatively charged ions, electrons and neutral species (atoms, molecules), it divides to types; hot and cold plasma. Hot plasma or non-equilibrium plasma consists of very high temperature particles and