Serum Bilirubin, Protein, and Ceruloplasmin in Acute Myocardial Infarction

Abstract

Objective: A prospective study carried out to assess serum levels of bilirubin, protein, and ceruloplasmin of 50 consecutive patients of myocardial infarction (AMI) with age ranges between 35-74 years (49.54±8.17),45 were males and 10 were females. Patient and methods: Fifty consecutive cases with symptoms and signs suggestive of AMI admitted to ICCU their age ranges between 35-74 year (49.54 ± 8.17), 41 were males and 9 were females. These patients supported by ECG and cardiac markers. Blood samples (5ml) were collected for analysis during 72 hours of admission at 9 a.m. Forty of healthy Iraqi volunteers of age- and sex-matched as a compared groups without any disease were enrolled. Results: Results showed that serum bilirubin and ceruloplasmin were significant higher among patient group (P=0.005) and (P<0.001) than that of control group, respectively, while serum protein was significant lower among patient group (P<0.00 1) than that of control group. Conclusion: Intravascular antioxidant i.e., serum total bilirubin and serum ceruloplasmin were significantly higher in Iraqi's patients with AMI than those of control group. Conversely, serum total protein concentrations were lower than those of control group. Therefore, serum bilirubin and serum ceruloplasmin may be considered biochemical risk factors for AMI. Key words : Serum billirubin, protein, ceruloplasmin ,acute myocardial Infarction