Synthesis, Characterization, Theoretical and Antimicrobial Evaluation of New Mn(II), Cu(II) and Zn(II) Complexes of Flavylium Salt

Abstract

A new series of Mn(II), Cu(II) and Zn(II) complexes with the two ligands were prepared and spectroscopic method and elemental analysis verified their structures. The first ligand L1 is flavylium salt and the second L2 is a Flavon. Reaction between transition metal salts and the ligands have synthesized two groups of new metal complexes. These complexes have been identified by available spectroscopic tools (UV-visible and IR) the C.H.N results confirmed the proposed structures. The experimental data disclosed that the complexes were coordinated by 6-the coordinate with mono-and bidentate ligands forming octahedral structure, in which L2 acts as monodentate and L1, L2 as bidentate ligands. The metal linked with L1 through the oxygen in ortho position in ring B, were as the linkage of the metal with L3 takes place through the oxygen of the carbonyl group. A theoretical treatment of the formation of complexes in the gas phase was studied, this was done using the HYPERCHEM-6 program for the Molecular mechanics and Semi-empirical calculations. The antimicrobial activity of the ligand and its metal complexes were studied against the following strains of microorganism: Staphylococcus aureus and Escherichia coli by the well diffusion method. Metal complexes showed enhanced antimicrobial activity compared with that of the free ligand.