Study of Toxoplasma infection in women recurrent abortion in First trimester of pregnancy by Indirect immunoflurescent antibody test (IFAT)

Abstract

During a period of six months, 50 blood samples were collected from women the occupation were Housewife in First trimester of pregnancy who were referred to the Maternity and Child Hospital in Ramadi , in addition to 50 samples from healthy women as control. All women were screened for Toxoplasma antibodies by latex agglutination test to study the positive rate of toxoplasmosis in the community and to investigate the effect of the risk factors on the positive rate of the disease. Toxoplasma -IgM antibodies were demonstrated by using IFAT to distinguish between acute and chronic infections. The overall seroprevalence of toxoplasmosis was 50%. The Toxoplasma antibodies increased with age especially in the age groups (26-30-31-35) years. Most of the positive women showed the highest titers 320 IU/ml especially in age group 26- 30, 31-35 years. Were recorded high number for abortion (30) from total number (50) . IFAT test was evaluated for specific IgM when testing 50 sera, 15 cases were with acute infection and 25with chronic toxoplasmosis using IFAT .