Synthesis and Characterization Complexes Of Cr(III),Mo(V) and W(VI) with Schiff Base Derivatives from (2-hydroxy-benzylidene) and Urea or Thiourea and Study of its biological activity.

Abstract

This study included synthesis of Schiff base ligands (2-hydroxy-benzylidene)- thiourea = (L1), (2-hydroxy-benzylidene)- urea = (L2) , the ligands were prepared from reaction (2-hydroxy benzylidene ) with urea or thiourea. Metal complexes of these ligands with some of transition metal ions Cr+3, Mo+5 and W+6 have been prepared and characterized by their (C.H.N) elemental analysis, IR, UV-VIS, atomic absorption, Molar conductivity measurements and melting points. From the result probable structures of the prepared complexes were proposed .Also includes, the study of biological effect for these complexes on four deferent pathogenic species : ( Streptococcus paecalies, Staphylococcus aureus),(Escherichia coli, Klebsiella Peneumonia ) . the first and second species are Gram positive while the other are Gram negative (by using agar well diffusion method). Finally ,it was found that compounds show different activity of inhibition on growth of the bacteria.