Biogenic Synthesis of Silver Nanoparticles and Study their Effect with Amoxicillin against Salmonella typhi and S. typhimurium

Abstract

The emergence of antibiotic- and /or multidrug-resistant bacteria is recognized as a crucial challenge for public health. The potential of AgNps as an anti-microbial agent is greatly investigated which considered as an alternative method to decrease multi-drug resistance microbes. AgNPs can offer a new strategy to tackle multidrug-resistant bacteria. The present study discusses the novel approach to synthesize nanoparticles involving biogenic synthesis of AgNPs using Klebsiella pneumoniae and study their impact as antimicrobial spectrum .The combined effect of silver nanoparticles with Amoxicillin against S. typhi and S. typhimurium was also observed . These tactics are used to promote antimicrobial efficacy of silver nanoparticles by modification of surfaces and to survey activity of antibiotic acceptance.