Physiological and immunological examination of hepatitis B virus (HBV)

Abstract

Background The large spread of viral hepatitis and the infection of many age groups, young people and the elderly in conditions of lack of awareness of the seriousness of this disease, it would have been better to shed light on this disease. Methodology Samples were collected from patients suffering from hepatitis B virus after diagnosing the disease using the ELISA device, where the number of infected reached 20 patients. In contrast, samples were collected from 20 others who were not infected as a control, Many physiological tests were performed, including WBC count, CRP GOT GPT and alkaline phosphatase The concentrations of interleukin 10 and 2 were measured using an ELISA device and compared with the control. Result there was an increase in the number of white blood cells, which reached 9480 cells per ml in the infected when compared to the control group, which had 4700 cells per ml. The concentration of C-reactive protein in the infected was also higher, at 24 mg/ml, indicating that viral hepatitis has an effect on some physiological variables compared to the control 6 mg 100 ml, as well as for the other variables GOT and GPT, there was a rise in their concentrations when compared to the control, the effect of viral hepatitis on interleukin 2 and 10 concentrations, which increased to 10. 24 and 10.5 in each case, respectively, when compared to control 2, 5, indicating that infection of liver cells with this virus stimulated immune cells to secrete these immunocytokines as part of an immune response.