Evaluation study of the anti-ulcer activities of Cuminum cyminum Seed extract against ethanolinduced gastric ulcer in rats.

Abstract

A herbaceous and pharmaceutical plant Cuminum cyminum L is one of crop and famous international spice seed after black pepper. This work was conducted to evaluate the effect the plant seeds extract against ulcer in the stomach. To achieve this goal, fifty-five rats were isolated into five gatherings. Individually, every one of the studied rats was pre-treated by oral administration with water and omeprazole and 20 mg, 250, 500 and 800 mg per kilogram of plant extracts to rat for 60 min. After that the rats were treated with ethanol to induce gastric mucosal damage. After a period for another 60 min, the rats were anesthetized and sacrificed.