Study of Some Biochemical Parameters in Iraqi Type II Diabetics Patients

Abstract

Background: Diabetes mellitus is a metabolic disorder characterized by hyperglycemia due to impairment of insulin secretion, defective insulin action, or both. Aim of study: The current study was planned to determine the serum levels of some biochemical parameters FSG, Hba1c, Lipid profile, and Renal functions in type 2 diabetics (T2D). Methods: Twenty-one Iraqi T2D patients and 21 control subjects matched for age and ethnic background were also included randomly selected from those attending Diabetes Center for Treatment at Ramadi General Hospital for the period from beginning November 2017 to the end of May 2018. Result:The mean levels of Blood pressure, FSG, HbA1c, Cholesterol, TG, LDL, VLDL, and S.Cr showed highly significant increase in group B Compared to A as well as the mean levels of HDL, T.P, Alb/Cr ratio and globulin showed highly significant decrease in group B compared to A. In contrast showed no statistical significant in mean levels of Age, WHr ratio, THr ratio, urea, UA, Albumin, Ca and Mg between group B and A.The receiver operator curve (ROC) investigation of the anticipated varieties uncovered the slipping request of HbA1c, FSG, TP, TG, VLDL, HDL, Cholesterol, LDL, Globulin, Alb/Cr ratio, Albumin, Cr, UA, Alb/Gratio, Urea, Ca, WHr ratio, THr ratio and Mg respectively that showed significant variation. In conclusion, high level of HbA1c%, FSG, TG, VLDL, Total Cholesterol, LDL, SCr, SUA and low levels of T.P, HDL, S.Globulin, Alb/Cr ratio, and S.Albumin were associated with an increased risk of T2DM, especially in obese Iraqi diabetics