Additions Effect of Vitamins A and E and Vaccination by Eimeria maxima Vaccine locally Produced on clinical signs, lesion score and Performance of broilers

Abstract

Abstract The aim of this research was study immunoeficiency of Eimeria maxima irradiated oocysts which attenuated by Gamma irradiation 200 gray through the vaccination of the birds with 8000 attenuated oocysts/ ml/ chick and the roles of vitamins A and E in improvement of immune response and birds performance. Two hundred and ten day– old Lohmann male birds were used in this experiment divided into 7 treatment with 2 replicate each replicate consist 15 birds. At tenth days of the age the birds were treated as follows: First treatment T1 were non vaccinated and non challenged, second treatment T2 were non vaccinated, third treatment T3 were vaccinated only, fourth treatment T4 were vaccinated and gave Vitamin A, fifth treatment T5 were Vaccinated and gave Vitamin E, sixth treatment T6 were vaccinated and gave Vitamin A and E combined and in the seventh treatment T7 were gave 8000 viable oocyst/ ml/ chick. The birds in treatment T2, T3, T4, T5, T6, T7 were challenged at thirty eight days of age with 40000 viable oocysts Eimeria maxima/ ml/ chick. Clinical signs, lesion score, body weight, feed conversion efficiency, mortality rate and feed consumptions were recorded one week after vaccination, one day before challenge and one week after challenge. Results showed that vaccination of birds with Eimeria maxime vaccine locally produced and the addition of vitamins A or E in as much (6-300) mg/ kg feed respectively singular or combined in the feed were gave significant (p<0.05) reduced in clinical signs, lesion score and significant (p<0.05) improvement in body weight, feed conversion efficiency, mortality rate and feed consumptions after challenge test.