Association of Vitamin D3 with some Biochemical Parameters in Benign Prostatic Hyperplasia Patients

Abstract

Benign prostatic hyperplasia is a common disease in nearly half of men between the ages of 51 and 60year, and this percentage increases to 90% of men over the age of 80 year. The study included (87 samples) divided into two groups of 25 healthy and 62 Benign prostatic hyperplasia patients. The study was conducted at Yarmouk Teaching Hospital (Baghdad) and the study period was from December 2019 to March 2020. By diagnosing vitamin D3, a similar deficiency in vitamin D3 was observed for the same target age group during the study and by observing healthy people of the same age group who had normal levels of vitamin D3 and found that 76% of them did not suffer from Benign prostatic hyperplasia problems. Through studying the variables, it was found that there is a negative relationship between the same statistical significance between vitamin D levels and prostatic specific antigen levels; and this relationship between them supports the relationship and the effect of vitamin D in reducing inflation, as prostate antigen levels rise in the case of inflation. The study of the relationships between the rest of the variables also showed a negative relationship between the level of the ratio of free prostate-free antigen to the total and the prostate-specific antigen; and this relationship is very important in differentiating between benign and malignant tumors in the prostate. The results of the study showed significant differences between the group of patients suffering from Benign prostatic hyperplasia and the group of healthy people in each of (vitamin D3, PSA, PTH, Serum Zinc, IV Age), while there were no significant differences between the two groups in each of (BMI, Testosterone, Calcium Ion, Phosphorus Ion, Serum Iron).