Study The effect of Some Hormones in Sera of Alopecia Areata Patients in Al-Ramadi City

Abstract

Alopecia areata is an autoimmune or organic disease that occur hair loss, and alopecia areata is characterized by patchy hair loss, which includes the scalp and other areas of the head, including eyelashes, beard and entire body hair, which may also be affected. A patient with alopecia areata notes the sudden appearance of a circular patch of hair loss, which may lead to baldness of the entire scalp and is called (Alopecia areata totalis) or loss of full body hair called (Alopecia areata universals). The etiopathogenesis of the disease is still unclear, but the role of autoimmunity is strongly suggested. AA is commonly associated with Thyroid disorders; the most frequent among them is autoimmune thyroid disorders. The aim of our study to determine whether Alopecia Areata (AA) is associated with some hormone like: Thyroid hormones ( T3, T4 and TSH ) Follicle Stimulating Hormone ( FSH ) and Luteinizing Hormones ( LH ) in patients with AA in Al- Ramadi city environment. The study includes 72 cases with age ranging from (10-50 years) ; (Group A) 42 patients with AA (27 male and 15 female) and (Group B) 30 healthy volunteers ( 7 male and 23 female ) are selected as a control group. All samples are obtained from Dermatology outpatient clinic, Al-Ramadi Hospital, Al-Anbar Governorate, Iraq. during the period from December 2019 to march 2020. Every case and control are subjected to history taking, dermatological examination and complete general Venous blood samples are taken from controls and patients after taking their agreement for measurement of some hormones such; Thyroid Hormones (TSH, T3, T4) and LH, FSH. We found, there were statistically significant differences between patients and controls regarding Thyroid Hormones levels of TSH, T3 and T4. ii Also There were significant differences between Patients and controls regarding of Follicle Stimulating Hormone ( FSH ) and Luteinizing Hormones ( LH ) So, Follow the current study with same parameters with more samples number to confirm the current results and It’s preferable to screened of Hormones every patient with Alopecia Areata such as thyroid hormones (TSH, T3, T4), Follicle Stimulating Hormone ( FSH ) and Luteinizing Hormones ( LH ) ,even in absence of manifestations suggestive of Hormone disorders and associated diseases.