Study The Effect of Ginger Oil on Plasmid Content and Biofilm of Staphylococcus aureus and Escherichia coli That Isolated From The Teeth

Abstract

The study included collection of 52 clinical samples from patients suffering from teeth infections, Microscopic and biochemical tests was conducted and a selective media were used for the diagnosis of bacterial isolates that isolated from the teeth. The results of this study showed abacterial isolates Staphylococcus aureus arate 21.3%, while the Escherichia coli were 10.7%. The effect of fourteen antibiotic was studied on all bacterial isolates which were 48 isolates by disk diffusion method and two isolates were represented the most resistant to antibiotics that was possessed pattern of multiple drug resistance towards(11-12) antibiotic among fourteen counter. The biofilm formation of the two bacterial species was investigated, the results showed the ability of all isolates to formation abiofilm. The oil was extracted from the collected and diagnosed ginger cellular toxicity, ph and the minimum inhibitory concentration were be tested toward the bacteria. The results of the statistical analysis showed that the isolates lost the ability to produce biofilm. The ability of oil to neutralize plasmids was tested and results showed the ability of ginger oil to neutralize plasmids.