Effect of Vitamin D Levels on Hormonal Profile in Infertile Women in Al-Anbar Governorate

Abstract

Infertility is the inability to become pregnant after one year of intercourse without using contraceptives, and it is of two types (primary and secondary). Primary infertility: is the infertility that affects a woman since the beginning of her sexual life or marriage. Secondary infertility: It is infertility that affects a woman after giving birth to a child or a pregnancy that ended in a miscarriage or an ectopic pregnancy. The aim of this study was to assess the prevalence of vitamin D deficiency among infertile women. In this study, an interview was conducted to fill out the questionnaire, where the study was conducted on 101 women who were divided into two groups: the healthy group included 40 healthy women, and the infertile group included 61 women (30 women with type 1 infertility and 31 women with type 2 infertility) their ages ranged between 18- 45 years old) was collected from Al-Razi Hospital in Ramadi during the period from October 2020 to April 2021. In conclusion, the levels of vitamin D in the group of infertile women of both types I and II were significantly lower compared to the fertile women (38.56 ± 1.48, 13.91 ± 1.07, 13.55 ± 1.21 ng/ml, respectively). In terms of age, we did not find a significant difference between the group of patients and healthy subjects, the mean BMI, increased significantly in the group of infertile patients compared to the healthy group, as well as the average waist-to-waist ratio, waist-to hip and systolic blood pressure increased significantly in the group of infertile women compared to the healthy group. VII Also, the levels of LH, PRL, and TT were significantly increased in the group of infertile women compared to the healthy ones, while an insignificant difference was observed in the level of TSH and FSH between the group of infertile and healthy women, while the level of AMH and E2 decreased significantly and significantly in the control group. Infertile women compared to fertile women. According to Pearson's analysis, a positive correlation was observed between vitamin D and AMH and E2, and a negative correlation was observed between vitamin D and each of: LH, PRL, TT, BMI, WHR, WWR, SBP, LH/FSH.