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Title: | A molecular-based approach to investigate breast cancer 1 and breast cancer 2 status in ovarian cancer among Iraqi women |
Authors: | MUHANNAD SHWEASH, SADDAM JUMAA NASEER MAISAM KHIDER AL-ANI, THULFIQAR FAWWAZ MUTAR |
Keywords: | Breast cancer 1 Breast cancer 2 Mutation Ovarian cancer Polymerase chain reaction |
Issue Date: | 3-Apr-2018 |
Publisher: | Asian J Pharm Clin Res - Innovare Academic Sciences Pvt Ltd |
Abstract: | Cancer ovary is one of the fatal gynecologic malignancies worldwide. Since breast cancer (BRCA) genes are considered tumor suppressor genes and play important roles in cancer by repairing of chromosomal damage with the error repair of DNA breaks. Therefore, breast cancer 1 (BRCA1) and breast cancer 2 (BRCA2) gene mutations strongly enhance the development of ovarian cancer risk among women. Here, we report that both genes are an essential mediator of progress ovarian cancer, to determine the influence of BRCA1 and BRCA2 mutations in the improvement of ovarian cancer. |
URI: | http://localhost:8080/xmlui/handle/123456789/9335 |
ISSN: | Vol 11, Issue 7, 2018, 199-204 |
Appears in Collections: | كلية الصيدلة |
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